Curcumin Solution is a high-tech formulation containing curcumin, the most biologically active ingredient in turmeric. It has been developed to maximise curcumin absorption and to enable its potential to be fully exploited.
Numerous studies have demonstrated curcumin’s exceptional properties, particularly in relation to inflammation and mutations that cause cell proliferation, now available to buy at Supersmart.
How does Curcumin Solution differ from other curcumin supplements?
Curcumin is an exceptional natural molecule, but its efficacy depends on the amount absorbed by the body. Absorption is normally very low due to its instability in acid conditions, poor solubility in digestive fluids and difficulty crossing the intestinal wall (10-12).
The advantage offered by Curcumin Solution is that it significantly increases this absorption by micronizing the curcumin and making it soluble in digestive fluids using micelles (microscopic beads that mix easily in water). This is a highly ingenious process: it increases curcumin’s ability to cross the intestinal wall by a factor of 185 compared with standard curcumin. This huge increase in absorption raises the amount of curcumin circulating in, and retained by, the body (curcumin’s half-life is normally very short). By way of comparison, all other strategies employed to increase its absorption are less effective: with the addition of piperine, for example, its absorption is only multiplied 20-30 times (13-14), while incorporating curcumin into lecithin liposomes barely increases it by a factor of four.
An independent study has demonstrated that Curcumin Solution is indeed the most bioavailable curcumin supplement on the market (15).
How does curcumin act in the body?
Curcumin is the most biologically active compound in the rhizome of Curcuma longa. It has an impressive number of biological benefits and acts against multiple cellular targets involved in cancer (16), diabetes (17), cardiovascular problems (18-20), neurodegenerative diseases (21), rheumatism (22), etc. Its effects on inflammation and elevated blood lipids have been demonstrated in several animal and human studies (23-25). In particular, it inhibits cholesterol production by the liver (26) and reduces the absorption of dietary cholesterol (27-29).
But the property which most interests' researchers is curcumin’s ability to inhibit the proliferation of cancer cells. It does so by intervening at various points in their development and by stimulating the production of enzymes that facilitate their elimination (30). The problem is that the amounts shown by in vitro tests to be effective are difficult to achieve in the body - which is precisely why Curcumin Solution has been developed – to maximise its absorption.
In 2018, researchers took a giant leap forward when they identified the effects of curcumin on a protein involved in cancer cells (31).
Note: It’s important to point out that Curcumin Solution 60 Licaps™ is not meant to rival the supplement Super Curcuma 500mg, one of the best products in our catalogue and one which regularly receives high praise from our customers. Curcumin Solution 60 Licaps™ is designed more to produce systemic benefits as the curcumin it contains reaches the bloodstream more easily. As far as the digestive system is concerned, Super Curcuma 500mg remains without doubt the best turmeric supplement on the market because it concentrates the curcumin more specifically in this area.
Daily dose: 2 Licaps™
Number of doses per pack: 30 |
Amount per dose |
NovaSOL® Curcumin (a blend standardised to 6% curcuminoids, comprising polysorbate and extract of Curcuma longa) |
1000 mg |
NovaSOL® Curcumin, Aquanova AG, Germany.
LICAPS™ & logo are trademarks of Lonza or its affiliates.
|
Adults. Take 2 Licaps™ a day.
Each Licaps™ capsule contains 500mg of NovaSOL® Curcumin.
- Alexa Kocher, Laura Bohnert, Christina Schiborr and Jan Frank, Mol. Nutr. Food Res. 2016, 60, 1555–1563 DOI 10.1002/mnfr.201501034 1555 RESEARCH ARTICLE Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidemic individuals k
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- Anand, K., Sarkar, A., Kumar, A., Ambasta, R. K. et al., Combinatorial antitumor effect of naringenin and curcumin elicit angioinhibitory activities in vivo. Nutr. 2012, 64, 714– 724.
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- Schiborr, C., Kocher, A., Behnam, D., Jandasek, J. et al., The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes. Mol. Nutr. Food Res. 2014, 58, 516–527.
- Kocher, A., Schiborr, C., Behnam, D., Frank, J., The Oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol. J. Functional Foods 2015, 14, 183–191
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